Articles
  • Surface modification of magnetite nanoparticles for immobilization with lysozyme 
  • M.-J. Kima, B. Lima, Y.-K. Jeongb, Y.W. Choa and Y.-H. Choaa,*
  • a College of Engineering Sciences, Hanyang University, Gyeonggi 426-791, Korea b National Core Research Center for Hybride Materials Solution, Pusan University
Abstract
The surface of magnetite (Fe3O4) nanoparticles prepared by a co-precipitation method was modified by the carboxylic acid group of meso-2,3-dimercaptosuccinic acid (DMSA). The egg white lysozyme was then immobilized on the carboxylic acid group-modified magnetite nanoparticles. The magnetite nanoparticles were approximately 10 nm and had a spherical morphology and uniform size distribution. The concentration of lysozyme on the modified magnetite nanoparticles was also investigated by a UV-Vis spectrometer and compared to that of magnetite nanoparticles without surface modification.

Keywords: magnetite nanoparticles; lysozyme; protein immobilization

This Article

  • 2007; 8(4): 293-295

    Published on Aug 31, 2007