Articles
  • Physicochemical properties and antibacterial studies of hydroxyapatite scaffold extracted from indonesian limestone

  • Juliasih Partinia, Silma Maula Bilqisa, Fikri Addin Salimya, Ihwanul Azizb, Mona Saric, Nilam Cahyatia and Yusril Yusuf a,*

  • aDepartment of Physics, Faculty of Mathematics and Natural Science, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
    bResearch Center of Accelerator Technology, Research Organization of Nuclear Energy, National Research and Innovation Agency (BRIN), Yogyakarta, Indonesia
    cDepartment of Physics Education, Faculty of Mathematics and Natural Science, Universitas Negeri Yogyakarta, Yogyakarta 55281, Indonesia

  • This article is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This research successfully fabricated scaffolds with hydroxyapatite (HA) from limestone and with HA coating using the gas foaming method. HA coating uses the addition of cinnamon oil in HA from limestone and impacts the scaffold’s antibacterial properties. Scaffold fabrication uses the gas foaming method with a drying time of 30 minutes and 0.9 grams of HA. The fabricated scaffold is then characterized using an X-ray diffractometer (XRD), Fourier Transform Infra-Red (FTIR), and Scanning Electron Microscopy (SEM). Then, the antibacterial analysis of scaffolds using the diffusion method. Scaffolds from HA coating have smaller crystal sizes, fewer agglomerations, smaller particle sizes, and a more even distribution and size of pores. Scaffolds with HA coating have higher porosity than scaffolds with HA only. HA coating shows that adding cinnamon oil as an antibacterial agent can inhibit strong bacteria for S. aureus bacteria with an inhibition zone size of 11 mm.


Keywords: Limestone, Hydroxyapatite, Gas foaming, Scaffold, Antibacterial.

This Article

  • 2024; 25(4): 599-606

    Published on Aug 31, 2024

  • 10.36410/jcpr.2024.25.4.599
  • Received on Mar 11, 2024
  • Revised on Jun 5, 2024
  • Accepted on Jun 7, 2024

Correspondence to

  • Yusril Yusuf

  • Department of Physics, Faculty of Mathematics and Natural Science, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
    Tel : +62-0274-6492383 Fax: +62-0274-6492383

  • E-mail: yusril@ugm.ac.id