Articles
  • Hydroxyapatite production and characterization from four pufferfish species teeth

  • Servet Ahmet Doğdua,b,*, Cemal Turanb, Tolga Depcic, Ersin Bahçecid, Kemal Sangüne and Deniz Ayasf

  • aIskenderun Technical University, Maritime Vocational School of Higher Education, Underwater Technologies, TR-31200, Hatay, Türkiye
    bIskenderun Technical University, Faculty of Marine Sciences and Technology, Molecular Ecology and Fisheries Genetics Laboratory, TR-31200 Iskenderun, Hatay, Türkiye
    cDepartment of Petrol and Natural Gases Engineering, Iskenderun Technical University, Iskenderun, Hatay, TR-31200, Türkiye
    dMetallurgical and Material Eng Engineering Department, Iskenderun Technical University, Iskenderun, Hatay, TR-31200, Türkiye
    eHatay Mustafa Kemal University, Faculty of Arts and Sciences, Department of Chemistry, Hatay, TR-31060, Türkiye
    fMersin University, Fisheries Faculty, Fishing and Seafood Processing Technology Department, Mersin, TR-33010, Türkiye

  • This article is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The pufferfishes are invasive alien fish species in the Mediterranean Sea with a powerful toxin in its body called tetrodotoxin. It has no economic value and is very abundant all over the world’s marine waters. Calcium phosphate bioceramic materials especially hydroxyapatite are commonly applied as implant resources because of their close resemblance in structure with natural bone. In this study, natural hydroxyapatite was obtained from the teeth of four pufferfish, the obtained products were characterised and their potential uses in the biomedical industry were revealed. Pufferfish teeth were extracted from the fish, thoroughly rinsed using deionized water, measured, and subsequently placed within a furnace set at a temperature of 105 °C. Once dehydrated, the teeth were finely pulverized using a planetary ball mill. This powdered material was then subjected to various analyses, including elemental composition assessment, TTX analysis, and SEM-EDX examinations. Ca/P atomic ratio values of Lagocephalus suezensis, L. guentheri, Sphoeroides pachygaster and Torguigener favimaculasus teeth were obtained as 1.58, 1.64, 1.67 and 1.47, respectively. The analysis findings suggest that pufferfish teeth could serve as a promising natural alternative source for biomedical and various other industries in need of natural hydroxyapatite. This hydroxyapatite can be utilized for creating fillers, implants, bone powder, and prostheses with applications in biomedicine and various industries. However, it should not be forgotten that the necessary tests must be carried out before any human use is made available.


Keywords: Calcium phosphate bioceramic, Blue biomaterials, Teeth, Pufferfish, Hydroxyapatite.

This Article

  • 2024; 25(1): 85-91

    Published on Feb 29, 2024

  • 10.36410/jcpr.2024.25.1.85
  • Received on Nov 19, 2023
  • Revised on Jan 2, 2024
  • Accepted on Jan 18, 2024

Correspondence to

  • Servet Ahmet Doğdu

  • aIskenderun Technical University, Maritime Vocational School of Higher Education, Underwater Technologies, TR-31200, Hatay, Türkiye
    bIskenderun Technical University, Faculty of Marine Sciences and Technology, Molecular Ecology and Fisheries Genetics Laboratory, TR-31200 Iskenderun, Hatay, Türkiye
    Tel : +90-542-311-11-05 Fax: +90-326-613-56-13

  • E-mail: servet.dogdu@iste.edu.tr