A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-Rallografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.
Keywords: calcium phosphate, bone cement, allograft, octacalcium phosphate, cell adhesion